遺伝研の客員教授であるDr. Arndt von Haeselerが来訪し、遺伝研でセミナーをしました。
セミナーは、次世代シーケンサーによって決定される塩基配列断片のマッピングの新しいアルゴリズムの話でした。
Monday, August 26, 2013, 16:00 - 17:00
Seminar Room, Main build. 3F, A316
Arndt von Haeseler (Center for Integrative Bioinformatics Vienna (CIBIV))
"NextGenMap: Fast and accurate read mapping in highly polymorphic genomes"
When choosing a read mapper, one faces the trade off between speed and the ability to map reads in highly polymorphic regions. Here we report NextGenMap, a fast and accurate read mapper, which reduces this dilemma. NextGenMap aligns reads reliably to a reference genome even when the sequence difference between target and reference genome is large i.e. highly polymorphic genome. At the same time, NextGenMap outperforms current mapping methods with respect to run time and to the number of correctly mapped reads. NextGenMap efficiently utilizes the available hardware by exploiting multi-core CPUs as well as graphic cards (GPUs), if available. In addition, NextGenMap handles automatically any read data independent of read length and sequencing technology.
